(±)13,14-EDT |
| カタログ番号GC91065 |
アドレニック酸の代謝産物
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 355016-19-2
Sample solution is provided at 25 µL, 10mM.
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(±)13,14-EDT is an oxylipin and a metabolite of adrenic acid formed via the cytochrome P450 (CYP) pathway.1,2 It activates large-conductance calcium-activated potassium channels (KCa1.1/BK) in isolated rat coronary small arterial smooth muscle cells when used at a concentration of 50 nM and induces dilation of isolated porcine arterioles (EC50 = 12 pM).3 (±)13,14-EDT also induces relaxation of isolated bovine coronary arteries precontracted with the TP receptor agonist U-46619 .2
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