(±)9(10)-EpOME (Synonyms: Coronaric Acid, (±)9,10EODE, Leukotoxin) |
| カタログ番号GC40540 |
(±)9(10)-EpOMEは、好中球によって酸化バースト中に生成されるリノール酸の9,10-cisエポキシドです。
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Sample solution is provided at 25 µL, 10mM.
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(±)9(10)-EpOME is the 9,10-cis epoxide of linoleic acid, generated by neutrophils during the oxidative burst. It has been recovered from the lungs of hyperoxic rats and from humans with acute respiratory distress syndrome. Mitochondrial dysfunction is the main feature of (±)9(10)-EpOME cytotoxicity, which may be due to the diol metabolites as well as the parent epoxide.
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