18β-Glycyrrhetyl-3-O-sulfate |
| カタログ番号GC71042 |
18β-Glycyrrhetyl-3-O-sulfate（グリチルリチン酸3-O-（硫酸水素））は強力な2型11β-ヒドロキシステロイドデヒドロゲナーゼ（11β-HSD 2）阻害剤であり、ラット腎ミクロソームを用いた場合IC 50は0.10µMであった。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 10251-38-4
Sample solution is provided at 25 µL, 10mM.
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18β-Glycyrrhetyl-3-O-sulfate (Glycyrrhetic acid 3-O-(hydrogen sulfate)) is a potent type 2 11β-hydroxysteroid dehydrogenase (11β-HSD2) inhibitor with an IC50 of 0.10 µM using rat kidney microsome. 18β-Glycyrrhetyl-3-O-sulfate is the major metabolite of Glycyrrhetinic acid (GA). 18β-Glycyrrhetyl-3-O-sulfate is the substrate of organic anion transporter (OAT) 1 and OAT3. 18β-Glycyrrhetyl-3-O-sulfate has anti-inflammatory effects and has the potential for pseudohyperaldosteronism research.
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Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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