2,4-Diamino-6-hydroxypyrimidine (Synonyms: DAHP) |
| カタログ番号GC16996 |
2,4-ジアミノ-6-ヒドロキシピリミジンは、特異的な GTP シクロヒドロラーゼ I 阻害剤 (de novo プテリン合成における律速酵素) です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1956/6/4
Sample solution is provided at 25 µL, 10mM.
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2,4-Diamino-6-hydroxypyrimidine is a specific GTP cyclohydrolase I inhibitor (the rate-limiting enzyme in de novo pterin synthesis), blocks BH4 synthesis and suppresses NO production[1].
References:
[1]. Sung YJ, et al. 2,4-Diamino-6-hydroxypyrimidine, an inhibitor of GTP cyclohydrolase I, suppresses nitric oxide production by chicken macrophages. Int J Immunopharmacol. 1994 Feb;16(2):101-8.
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