23-epi-26-Deoxyactein (Synonyms: 27-Deoxyactein) |
| カタログ番号GC42091 |
23-epi-26-Deoxyactein は、Cimicifuga racemosa から分離された成分であり、TCDD による骨芽細胞の損傷を防ぎます。
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Cas No.: 264624-38-6
Sample solution is provided at 25 µL, 10mM.
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23-epi-26-Deoxyactein is a triterpene glycoside and a major constituent of black cohosh (C. racemosa). It reduces intracellular calcium concentrations, collapse of the mitochondrial membrane potential, production of reactive oxygen species (ROS), and cardiolipin peroxidation and inhibits autophagy and apoptosis in osteoblastic MC3T3-E1 cells induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). 23-epi-26-Deoxyactein (0.01-10 μM) reduces production of ROS and IL-1β and cell death induced by methylglyoxal in RIN-m5F β-cells.
Average Rating: 5 (Based on Reviews and 4 reference(s) in Google Scholar.)
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