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3α,7α-Dihydroxycoprostanic acid-d3

カタログ番号GC70356

3α,7α-Dihydroxycoprostanic acid-d3は重水素標識3α,7α−ジヒドロキシコステロール酸である。

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3α,7α-Dihydroxycoprostanic acid-d3 化学構造

Cas No.: 338976-76-4

サイズ 価格 在庫数 個数
500 µg
$504.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
3α,7α-Dihydroxycoprostanic acid-d3is the deuterium labeled3α,7α-Dihydroxycoprostanic acid. 3α,7α-Dihydroxycoprostanic acid is an endogenous metabolite. 3α,7α-Dihydroxycoprostanic acid, a bile acid, is the precursor to chenodeoxycholic acid.

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

References:
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

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