3-Bromotyrosine (trifluoroacetate salt) (Synonyms: 3-bromo-Tyr) |
| カタログ番号GC42251 |
3-ブロモチロシンは、アレルギー反応中に好酸球の活性化後に見つかるタンパク質の酸化生成物です。
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Cas No.: 2320428-62-2
Sample solution is provided at 25 µL, 10mM.
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3-Bromotyrosine is a product of protein oxidation found after activation of eosinophils during an allergic response. It has been used as a marker of eosinophil peroxidase-induced protein oxidation in vitro and in vivo. In addition to its production in eosinophils, 3-bromotyrosine is found at 5-fold higher levels in peritoneal exudate from mice infected with K. pneumoniae compared with uninfected animals, suggesting neutrophils release higher levels of oxidized products during inflammation. In a human study, 3-bromotyrosine was increased 10-fold in allergen-challenged lung samples from subjects with allergen-induced asthma.
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