3-Methylquinoxaline-2-carboxylic Acid (Synonyms: MQCA) |
| カタログ番号GC41619 |
キノセトンまたはオラキンドックスの重要な N-オキシド還元代謝産物である 3-メチルキノキサリン-2-カルボン酸 (MQCA) は、細胞周期の S 期停止により、チャン肝細胞の増殖を強力に阻害します。
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Cas No.: 74003-63-7
Sample solution is provided at 25 µL, 10mM.
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3-Methylquinoxaline-2-carboxylic acid (MQCA) is a major metabolite of olaquindox, an antibiotic and swine growth regulator. It induces cell cycle arrest at the S phase and is toxic to Chang liver cells in a concentration- and time-dependent manner. MQCA has been used as a marker of olaquindox use in livestock applications.
| Cas No. | 74003-63-7 | SDF | |
| 同義語 | MQCA | ||
| Canonical SMILES | CC1=NC2=CC=CC=C2N=C1C(O)=O | ||
| Formula | C10H8N2O2 | M.Wt | 188.2 |
| 溶解度 | DMF: 25 mg/mL,DMSO: 30 mg/mL,DMSO:PBS (pH 7.2) (1:10): 0.1 mg/mL,Ethanol: 25 mg/mL | Storage | Store at -20°C |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
|
1 mg | 5 mg | 10 mg |
| 1 mM | 5.3135 mL | 26.5675 mL | 53.135 mL |
| 5 mM | 1.0627 mL | 5.3135 mL | 10.627 mL |
| 10 mM | 0.5313 mL | 2.6567 mL | 5.3135 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 36 reference(s) in Google Scholar.)
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