4-Methylamphetamine (hydrochloride) (Synonyms: 4MA, p-Methylamphetamine, para-Methylamphetamine) |
カタログ番号GC42435 |
4-メチルアンフェタミン(4-MA)(塩酸塩)は、アンフェタミンに分類される解析用基準物質です。
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Cas No.: 41632-56-8
Sample solution is provided at 25 µL, 10mM.
4-Methylamphetamine (4-MA) (hydrochloride) is an analytical reference standard categorized as an amphetamine. 4-MA acts on norepinephrine (NE), dopamine (DA), and serotonin (5-HT) transporters to increase extracellular levels of these neurotransmitters. In vitro, the potencies of 4-MA for NE and DA release are similar to those of D-amphetamine with EC50 values of 22.2 and 7.2 nM for NE and 44.1 and 8.0 nM for DA, respectively. 4-MA is more potent than D-amphetamine at releasing serotonin (EC50s = 53.4 and 1,756 nM, respectively). In rats, 4-MA acts as an agonist at 5-HT1A receptors and induces hypothermia. It is found as a contaminant in amphetamine, and ingestion has been associated with severe intoxication and fatalities. This product is intended for research and forensic applications.
Average Rating: 5
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