ホーム>>Lipids>> Reactive O2/N2 Pathways>>8-iso Prostaglandin F1α-d9

8-iso Prostaglandin F1α-d9 (Synonyms: 8epi PGF1αd9)

カタログ番号GC46746

多様な生物学的活性を持つ神経ペプチド

Products are for research use only. Not for human use. We do not sell to patients.

8-iso Prostaglandin F1α-d9 化学構造

Cas No.: 26771-96-0

サイズ 価格 在庫数 個数
25 μg
$201.00
在庫あり
50 μg
$381.00
在庫あり
100 μg
$722.00
在庫あり

Tel:(909) 407-4943 Email: sales@glpbio.com


顧客レビュー

カスタマーレビューに基づきます。

  • GlpBio Citations

    GlpBio Citations
  • Bioactive Compounds Premium Provider

    Bioactive Compounds Premium Provider

Sample solution is provided at 25 µL, 10mM.

Description of 8-iso Prostaglandin F1α-d9

8-iso Prostaglandin F-d9 (8-iso PGF-d9) contains nine deuterium atoms at the 17, 17', 18, 18', 19, 19', 20, 20, and 20 positions. It is intended for use as an internal standard for the quantification of 8-iso PGF by GC- or LC-mass spectrometry. 8-iso PGF is an isoprostane that was first identified in human semen.1 It is a member of the isoprostane family, which are eicosanoids of non-cyclooxygenase origin. 8-iso PGF is present along with its 19-hydroxy congener at 5-10 µg/ml of seminal plasma.2

1.Svanborg, K., Bygdeman, M., and Eneroth, P.The F and 19-hydroxy F prostaglandins and their 8β-isomers in human seminal plasma: Data on chromatography and mass spectrometryBiomedical Mass Spectrometry10495-498(1983) 2.Taylor, P.L.The 8-isoprostaglandins: Evidence for eight compounds in human semenProstaglandins17259-267(1979)

Chemical Properties of 8-iso Prostaglandin F1α-d9

Cas No. 26771-96-0 SDF
同義語 8epi PGF1αd9
Canonical SMILES O[C@@H]1[C@@H](CCCCCCC(O)=O)[C@@H](/C=C/[C@@H](O)CC([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])[C@H](O)C1
Formula C20H27D9O5 M.Wt 365.6
溶解度 DMF: 50 mg/ml,DMSO: 50 mg/ml,Ethanol: 50 mg/ml,PBS (pH 7.2): 1 mg/ml Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of 8-iso Prostaglandin F1α-d9

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.7352 mL 13.6761 mL 27.3523 mL
5 mM 0.547 mL 2.7352 mL 5.4705 mL
10 mM 0.2735 mL 1.3676 mL 2.7352 mL
  • モルアリティ計算機

  • 希釈計算機

  • Molecular Weight Calculator

質量
=
濃度
x
容積
x
MW*
 
 
 
**ストックソリューションを準備する際には、常にバイアルラベルおよび MSDS/CoA(オンラインで利用可能)で掲載された製品のロット固有分子量を使用してください。

計算

In vivo Formulation Calculator (Clear solution) of 8-iso Prostaglandin F1α-d9

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

View current batch:

レビュー

Review for 8-iso Prostaglandin F1α-d9

Average Rating: 5 ★★★★★ (Based on Reviews and 39 reference(s) in Google Scholar.)

5 Star
100%
4 Star
0%
3 Star
0%
2 Star
0%
1 Star
0%
Review for 8-iso Prostaglandin F1α-d9

GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.

Required fields are marked with *

You may receive emails regarding this submission. Any emails will include the ability to opt-out of future communications.