8(S)-HETE (Synonyms: 8(S)-Hydroxyeicosatetraenoic Acid) |
| カタログ番号GC40463 |
8(S)-HETEは、PMA処理されたマウス表皮において主要なリポキシゲナーゼ生成物です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 98462-03-4
Sample solution is provided at 25 µL, 10mM.
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8(S)-HETE is a major lipoxygenase product in PMA-treated murine epidermis. It activates mouse keratinocyte protein kinase C with an IC50 of 100 µM. 8(S)-HETE also activates PPARα selectively at concentrations as low as 0.3 µM. Stereochemical assignment of the (S) enantiomer is based on comparison of chiral HPLC retention times to published results.
Average Rating: 5 (Based on Reviews and 1 reference(s) in Google Scholar.)
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