ABT 702 |
| カタログ番号GB40090 |
最初の非核酸ヌクレオシドアデノシンキナーゼ（ADK）阻害剤（細胞質および完全な細胞アッセイにおけるIC50値はそれぞれ2 nMおよび50 nM）。ABT702は動物モデルで疼痛や炎症を軽減するために経口的に投与されますが、in vitro中国ハムスターミクロ核試験では染色体異常原性が見られました。
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Cas No.: 214697-26-4
Sample solution is provided at 25 µL, 10mM.
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The first, non-nucleoside adenosine kinase (ADK) inhibitor (IC50 value 2 nM and 50 nM in cytosolic and intact cell assays, respectively). ABT702 is orally active to reduce pain and inflammation in animal models, yet found to be clastogenic in an in vitro Chinese Hamster micronucleus assay.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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