Ac-AAVALLPAVLLALLAP-DEVD-CHO (trifluoroacetate salt) (Synonyms: Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Asp-Glu-Val-Asp-CHO, Ac-AAVALLPAVLLALLAP-DEVD-aldehyde, Ac-AAVALLPAVLLALLAPDEVD-CHO, Caspase-3 Inhibitor I, DEVD-CHO-CPP 32) |
カタログ番号GC40122 |
Ac-AAVALLPAVLLALLAP-DEVD-CHOは、caspase-3および-7のペプチド阻害剤であるAc-DEVD-CHOと、K-FGFから派生した細胞浸透性疎水性配列を含む複合体です。
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
Ac-AAVALLPAVLLALLAP-DEVD-CHO is a composite of Ac-DEVD-CHO , a peptide inhibitor of caspase-3 and -7, and a cell-permeable hydrophobic sequence derived from K-FGF. It is an inhibitor of caspase-3 that reduces caspase-3 activity and apoptosis induced by prostaglandin E2 in rat cortical neurons when used at concentrations ranging from 1 to 2.5 μM.
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