Ac-Calpastatin (184-210) (Synonyms: Calpastatin Peptide B27-WT) |
カタログ番号GC40554 |
カルパインは、カルシウム依存性のシステインプロテアーゼのファミリーであり、μ-カルパイン(カルパインI)はマイクロモーラーのカルシウムを必要とし、m-カルパイン(カルパインII)はミリモーラーのカルシウムを必要とします。
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Cas No.: 79079-11-1
Sample solution is provided at 25 µL, 10mM.
The calpains are a family of calcium-dependent cysteine proteases, with calpain I (µ-calpain) requiring micromolar calcium and calpain II (m-calpain) requiring millimolar calcium. Ac-calpastatin (184-210) is an acetylated synthetic peptide from human calpastatin that strongly inhibits both calpains I and II but not papain (a cysteine protease) or trypsin (a serine protease). This 27 amino acid peptide is encoded by exon 1B of Ac-calpastatin (184-210) and corresponds to a portion of inhibitory domain 1.
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