Adenosine-5'-O-(2-thiodiphosphate) (sodium salt) |
| カタログ番号GC90795 |
P2Y受容体のアゴニスト
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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Adenosine-5'-O-(2-thiodiphosphate) is an agonist of purinergic P2Y receptors.1 It increases glucose-stimulated insulin release in isolated rat pancreas when used at concentrations ranging from 49.5 to 495 nM. Adenosine-5'-O-(2-thiodiphosphate) (1.5 µM) induces vasodilation in isolated rat pancreas and relaxation in isolated rat aortic rings precontracted by serotonin with an EC50 value of 0.09 µM.2 It increases insulin secretion and reduces elevated glucose levels in fasted dogs when administered at a dose of 0.1 mg/kg.3
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