Adrenomedullin (AM) (13-52), human |
| カタログ番号GC32622 |
アドレノメデュリン (AM) (13-52)、ヒトは、内皮依存性血管拡張剤として作用する 40 アミノ酸のペプチドです。
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Cas No.: 154765-05-6
Sample solution is provided at 25 µL, 10mM.
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Adrenomedullin (AM) (13-52), human is a 40 amino acid peptide, which acts as an endothelium-dependent vasodilator agent.
The effects of Adrenomedullin (AM) (13-52), human [hADM-(13-52)] are investigated in the rat pulmonary vascular bed and in isolated rings from the rat pulmonary artery (PA). Under conditions of controlled blood flow and constant left atrial pressure when tone is increased with U-46619, injection of hADM-(13-52) produces dose-related decreases in lobar arterial pressure. hADM-(13-52) modulates receptor-mediated, but not voltage-dependent, pulmonary vascular contraction by influencing Ca2+ influx[1].
[1]. Gumusel B, et al. Analysis of responses to adrenomedullin-(13-52) in the pulmonary vascular bed of rats. Am J Physiol. 1998 Apr;274(4 Pt 2):H1255-63.
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