AG 1478 (Base) (Synonyms: N-(3-Chlorophenyl)-6,7-dimethoxy-4-quinazolinanine, free base) |
| カタログ番号GB40094 |
AG-1478（175478-82-2; 塩基）は、EGFRキナーゼの強力で選択的な阻害剤です（IC50 = 3 nM）。様々な人間がん細胞株の増殖を抑制します。 AG-1478はラットモデルにおいて肺線維症を軽減します。細胞浸透性があります。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 175178-82-2
Sample solution is provided at 25 µL, 10mM.
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AG-1478 (175478-82-2; base) is a potent and selective inhibitor of the EGFR kinase (IC50 = 3 nM). Inhibits proliferation of a variety human cancer cell lines. AG-1478 reduces pulmonary fibrosis in a rat model. Cell permeable.
Review for AG 1478 (Base)
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
Review for AG 1478 (Base)
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