AGG-523 (Synonyms: AGG-523; AGG 523; AGG523; PF-05212371; PF 05212371; PF05212371; WAY-266523; WAY 266523; WAY266523;) |
| カタログ番号GB62287 |
AGG-523は、ラットMTモデルにおいて手術的に誘発された関節不安定性後の滑液ARG-アグレカンレベルの増加を抑制することが示されたアグレカナーゼ特異的阻害剤です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 920289-29-8
Sample solution is provided at 25 µL, 10mM.
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AGG-523 is an aggrecanase specific inhibitor that has been shown to attenuate increases in synovial fluid ARG-aggrecan levels following surgically-induced joint instability in the rat MT model. Pharmacologic inhibition of aggrecanase activity in humans using AGG-523 may be an effective treatment for slowing cartilage degradation following joint injury.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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