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Ald-CH2-PEG5-Boc

カタログ番号GC66606

Ald-CH2-PEG5-Boc は、PEG およびアルキル/エーテルベースの PROTAC リンカーであり、PROTAC の合成に使用できます。

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Ald-CH2-PEG5-Boc 化学構造

Cas No.: 1446282-23-0

サイズ 価格 在庫数 個数
100mg
$1,517.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

Ald-CH2-PEG5-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

[1]. Tovell H, et al. Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTAC Degrader. ACS Chem Biol. 2019 Sep 20;14(9):2024-2034.

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