ALX-1393 TFA |
カタログ番号GC70319 |
ALX-1393 TFA、ラット急性疼痛モデルにおいて熱、機械及び化学刺激に対する鎮痛作用を有する選択的GlyT 2阻害剤。
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Sample solution is provided at 25 µL, 10mM.
ALX-1393 TFA, a selective GlyT2 inhibitor, has an antinociceptive effect on thermal, mechanical, and chemical stimulations in a rat acute pain model.
ALX1393 TFA (i.c.v.; 25, 50, and 100 μg) in normal rats suppresses the late-phase response in the formalin test but does not affect motor performance. ALX1393 inhibits mechanical and cold hyperalgesia in a dose-dependent manner[2].
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