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Amylin (8-37) (human) (trifluoroacetate salt) (Synonyms: IAPP (8-37) (human), Islet Amyloid Polypeptide (8-37) (human))

カタログ番号GC42794

アミリン(8-37)は、アミリンのペプチド断片です。

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Amylin (8-37) (human) (trifluoroacetate salt) 化学構造

サイズ 価格 在庫数 個数
500μg
$506.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.

Description of Amylin (8-37) (human) (trifluoroacetate salt)

Amylin (8-37) is a peptide fragment of amylin . It inhibits osteoblast proliferation, but not bone resorption, induced by full-length human amylin and does not act as an agonist at amylin receptors. Amylin (8-37) induces formation of polymorphic fibrils containing coiled and laterally-associated sheet structures. It is cytotoxic to RINm5F islet β-cells in vitro when used at a concentration of 25 µM, an effect that is inversely correlated with mature fibril content.

Chemical Properties of Amylin (8-37) (human) (trifluoroacetate salt)

Cas No. SDF
同義語 IAPP (8-37) (human), Islet Amyloid Polypeptide (8-37) (human)
Formula C138H215N41O46•XCF3COOH M.Wt 3184.4
溶解度 Water: 1 mg/ml Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Amylin (8-37) (human) (trifluoroacetate salt)

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 0.314 mL 1.5702 mL 3.1403 mL
5 mM 0.0628 mL 0.314 mL 0.6281 mL
10 mM 0.0314 mL 0.157 mL 0.314 mL
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計算

In vivo Formulation Calculator (Clear solution) of Amylin (8-37) (human) (trifluoroacetate salt)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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Average Rating: 5 ★★★★★ (Based on Reviews and 8 reference(s) in Google Scholar.)

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