AN-2898 (Synonyms: AN-2898; AN 2898; AN2898.) |
カタログ番号GB62232 |
AN-2898は、真菌感染症の治療に有望な、強力で選択的なPDE4阻害剤です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 906673-33-4
Sample solution is provided at 25 µL, 10mM.
AN-2898 ia a potent and selective PDE4 inhibitor potentially for the treatment of fungal infection. AN2898 inhibited phosphodiesterase 4 (PDE4) enzyme activity (IC50 0.060 μM) and the release of multiple cytokines including TNF-α (IC50 0.16 μM) from peripheral blood mononuclear cells (hPBMCs) stimulated by lipopolysaccharide (LPS) or phytohemag- glutinin.
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(Based on Reviews and 30 reference(s) in Google Scholar.)Review for AN-2898
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