Apcin-A |
| カタログ番号GC62419 |
アプシン誘導体であるアプシン-Aは、後期促進複合体（APC）阻害剤です。 Apcin-A は Cdc20 と強く相互作用し、Cdc20 基質のユビキチン化を阻害します。 Apcin-A は、PROTAC CP5V の合成に使用できます。
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Cas No.: 1683617-62-0
Sample solution is provided at 25 µL, 10mM.
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Apcin-A, an Apcin derivative, is an anaphase-promoting complex (APC) inhibitor. Apcin-A interacts strongly with Cdc20, and inhibits the ubiquitination of Cdc20 substrates. Apcin-A can be used to synthesize the PROTAC CP5V [1].
[1]. Chi JJ, et al. A novel strategy to block mitotic progression for targeted therapy. EBioMedicine. 2019 Oct 25. pii: S2352-3964(19)30677-2.
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