Apraglutide (Synonyms: FE 203799) |
| カタログ番号GC34473 |
アプラグルチド (FE 203799)、合成 33 アミノ酸ペプチドおよび長時間作用型 GLP-2 類似体は、回腸の完全切除を伴う短腸症候群の新生児子豚モデルにおける適応および直線的な腸の成長を促進します 。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1295353-98-8
Sample solution is provided at 25 µL, 10mM.
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Apraglutide (FE 203799), a synthetic 33-amino-acid peptide and a long-acting GLP-2 analogue, enhances adaptation and linear intestinal growth in a neonatal piglet model of short bowel syndrome with total resection of the ileum[1].
Apraglutide (FE 203799; 5 mg/kg/dose, subcutaneously, twice on days 0 and 4 postsurgery) treated piglets are healthy, have significant lower fecal fat and energy losses and exhibite intestinal lengthening, greater small-intestinal weight, longer villus height, and greater crypt depth on day 7[1]. Animal Model: NewbornDuroc piglets, 2-5 days old and weighing between 2-2.6 kg[1].
[1]. Slim GM, et al. Novel Long-Acting GLP-2 Analogue, FE 203799 (Apraglutide), Enhances Adaptation and Linear Intestinal Growth in a Neonatal Piglet Model of Short Bowel Syndrome with Total Resection of the Ileum. JPEN J Parenter Enteral Nutr. 2019 Jan 6.
Average Rating: 5 (Based on Reviews and 21 reference(s) in Google Scholar.)
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