Atuzabrutinib |
| カタログ番号GC70685 |
Atuzabrutinib（SAR 444727）は、強力で選択的に可逆的なBtk（ブルトンチロシンキナーゼ）阻害剤である。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1581714-49-9
Sample solution is provided at 25 µL, 10mM.
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Atuzabrutinib (SAR 444727) is a potent, selective reversible inhibitor of Btk (Bruton's tyrosine kinase) inhibitor. Atuzabrutinib inhibits neutrophil recruitment via inhibition of macrophage antigen-1 signalling.
PRN473 (20 mg/kg) significantly reduces intravascular crawling and neutrophil recruitment into inflamed tissue in a model of sterile liver injury, down to levels seen in Btk-deficient animals[1].
Review for Atuzabrutinib
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
Review for Atuzabrutinib
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