AZ PFKFB3 26 |
| カタログ番号GC34479 |
AZ PFKFB3 26 は、代謝キナーゼ PFKFB3 の強力かつ選択的な阻害剤であり、IC50 は 23 nM です。 AZ PFKFB3 26 は、それぞれ 2.06 および 0.384 μM の IC50 で PFKFB1 および PFKFB2 を阻害します。
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Cas No.: 1704740-52-2
Sample solution is provided at 25 µL, 10mM.
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AZ PFKFB3 26 is a potent and selective inhibitor of the metabolic kinase PFKFB3 with an IC50 of 23 nM. AZ PFKFB3 26 inhibits PFKFB1 and PFKFB2 with IC50s of 2.06 and 0.384 μM, respectively[1]. IC50: 23 nM (PFKFB3), 2.06 μM (PFKFB1), 0.384 μM (PFKFB2)[1]
[1]. Boyd S, et al. Structure-Based Design of Potent and Selective Inhibitors of the Metabolic Kinase PFKFB3. J Med Chem. 2015 Apr 23;58(8):3611-25.
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