Azido-PEG8-Boc |
| カタログ番号GC61542 |
Azido-PEG8-Boc は、PEG およびアルキル/エーテルベースの PROTAC リンカーであり、PROTAC の合成に使用できます。
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Cas No.: 1623791-99-0
Sample solution is provided at 25 µL, 10mM.
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Azido-PEG8-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
[1]. Garofalo, Antonio, et al. Efficient synthesis of small-sized phosphonated dendrons: potential organic coatings of iron oxide nanoparticles. New Journal of Chemistry (2014), 38(11), 5226-5239.
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