Bepirovirsen sodium |
カタログ番号GC70990 |
Bepirovirsen sodiumは、すべてのhbvメッセンジャーrnaを標的とするアンチセンスオリゴヌクレオチドである。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2563929-84-8
Sample solution is provided at 25 µL, 10mM.
Bepirovirsen sodium is an antisense oligonucleotide targeting all HBV messenger RNAs. Bepirovirsen leads to reductions in HBV-derived RNAs, HBV DNA and viral proteins. Bepirovirsen sodium can be used for the research of chronic HBV infection. Bepirovirsen binding site sequence (GCACTTCGCTTCACCTCTGC).
References:
[1]. Yuen MF, et al. Safety, tolerability and antiviral activity of the antisense oligonucleotide bepirovirsen in patients with chronic hepatitis B: a phase 2 randomized controlled trial. Nat Med. 2021 Oct;27(10):1725-1734.
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