BFF 122 - BF 5 |
| カタログ番号GB40120 |
キヌレニンアミノトランスフェラーゼIIの強力で選択的な阻害剤（KAT IIおよびKAT Iに対するIC50値はそれぞれ約1μMおよび> 30μM）。内側尾状核に投与されたBFF122は、KYNAの新規形成を66％減少させましたが、ナイーブラットでは3-HKまたはQUINの生成に影響を与えませんでした。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1152314-49-2
Sample solution is provided at 25 µL, 10mM.
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Potent and selective inhibitor of kynurenine aminotransferase II (IC50 values ca. 1 μM and >30 μM for KAT II and KAT I respectively). Intrastriatal BFF 122 decreased newly formed KYNA by 66%, without influencing 3-HK or QUIN production in naÏve rats.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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