BMS 986187 |
| カタログ番号GC18823 |
δオピオイド受容体の陽性アロステリック調節因子
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 684238-37-7
Sample solution is provided at 25 µL, 10mM.
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BMS 986187 is a positive allosteric modulator of δ-opioid receptors. In the presence of the endogenous δ-opioid receptor agonist leu-enkephalin, BMS 986187 has an average EC50 value of 30 nM for β-arrestin recruitment, but has little to no activity in the absence of an agonist. It is 100-fold selective for δ- over u-opioid receptors in the presence of leu-enkephalin and the endogenous u-opioid receptor agonist endomorphin I, respectively.
Review for BMS 986187
Average Rating: 5 (Based on Reviews and 17 reference(s) in Google Scholar.)
Review for BMS 986187
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