Boc-NH-PEG2-CH2COOH |
| カタログ番号GC60653 |
HBC514 は非蛍光性の HBC 類似体ですが、Pepper RNA アプタマーと緊密な複合体を形成すると強い緑色の蛍光を発します。 HBC514-Pepper 複合体は、RNA の可視化を可能にし、Pepper でタグ付けされた生きた細胞での単純な洗浄と染色によって蛍光を柔軟に変更することができます 。
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Cas No.: 108466-89-3
Sample solution is provided at 25 µL, 10mM.
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Boc-NH-PEG2-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
[1]. Zhou F, et al. Development of selective mono or dual PROTAC degrader probe of CDK isoforms. Eur J Med Chem. 2020 Feb 1;187:111952.
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