Boc-NH-PEG5-CH2CH2COOH |
| カタログ番号GC60657 |
Boc-NH-PEG5-CH2CH2COOH は、PROTAC の合成に使用できる PEG ベースの PROTAC リンカーです。
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Cas No.: 1347750-78-0
Sample solution is provided at 25 µL, 10mM.
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Boc-NH-PEG5-CH2CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
[1]. Nathanael Gray, et al. Bifunctional compounds for her3 degradation and methods of use. WO2017117474A1.
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