Buserelin-NHNH2 (trifluoroacetate salt) |
| カタログ番号GC42991 |
ブセレリンは、少なくともGNRHの20倍以上の強さを持つ合成ゴナドトロピン放出ホルモン（GNRH）アゴニストです。
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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Buserelin is a synthetic gonadotropin-releasing hormone (GNRH) agonist that is at least 20 times more potent than GNRH. It is a long-acting agent that, after an initial increase in sex hormone levels, decreases the level of circulating gonadotropins and sex hormones. Buserelin (20 µg/kg) reduces tumor growth in a DMBA-induced rat model of mammary cancer. It induces enteric neurodegeneration, decreasing the number of luteinizing hormone receptor-positive neurons in the rat gastrointestinal tract, when administered at a dose of 1 mg/kg for 5 days. Formulations containing buserelin have been used in the treatment of hormone-dependent prostate cancer and endometriosis.
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