BV02 |
カタログ番号GC66461 |
BV02 は、強力な 4-3-3 PPI (14-3-3 タンパク質間相互作用) 阻害剤です。 BV02 は、IM (メシル酸イマチニブ) 感受性野生型 Bcr-Abl および IM 耐性 T315I 変異を発現する造血細胞に対する細胞毒性を示します。 BV02 は、慢性骨髄性白血病の研究の可能性を秘めています。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 292870-53-2
Sample solution is provided at 25 µL, 10mM.
BV02 is a potent 4-3-3 PPI (14-3-3 protein-protein interaction) inhibitor. BV02 shows cytotoxicity for hematopoietic cells expressing the IM (imatinib mesylate)-sensitive wild type Bcr-Abl and the IM-resistant T315I mutation. BV02 has the potential for the research of chronic myeloid leukemia[1][2].
Average Rating: 5
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