C10 Ceramide (d18:1/10:0) (Synonyms: N-decanoyl-D-erythro-Sphingosine) |
| カタログ番号GC43004 |
C10セラミドは、セラミドシンターゼによって生産される内因性のバイオアクティブスフィンゴリピッドです。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 111122-57-7
Sample solution is provided at 25 µL, 10mM.
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C10 ceramide is an endogenous, bioactive sphingolipid produced by ceramide synthase. [1] C10 ceramide inhibits growth of wild-type and MDR1 gene-transfected MDA435/LCC6 human breast cancer cells with IC50 values of 44.1 and 46 μM, respectively. It also inhibits the growth of J774 murine macrophages in a dose-dependent manner.
Reference:
[1]. Shabbits, J.A., and Mayer, L.D. Intracellular delivery of ceramide lipids via liposomes enhances apoptosis in vitro. Biochim Biophys. Acta. 1612(1), 98-106 (2003).
Average Rating: 5 (Based on Reviews and 37 reference(s) in Google Scholar.)
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