C108297 |
カタログ番号GC70575 |
C108297は選択的グルココルチコイド受容体(GR)調節剤(GR結合Ki 0.7 nM、GRレポーター遺伝子機能Ki 0.6 nM)である。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 864972-30-5
Sample solution is provided at 25 µL, 10mM.
References:
[1]. Clark RD, et al. 1H-Pyrazolo[3,4-g]hexahydro-isoquinolines as selective glucocorticoid receptor antagonists with high functional activity. Bioorg Med Chem Lett. 2008;18(4):1312-1317.
[2]. van den Heuvel JK, et al. Identification of a selective glucocorticoid receptor modulator that prevents both diet-induced obesity and inflammation. Br J Pharmacol. 2016;173(11):1793-1804.
Average Rating: 5
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