CA/MAO-B-IN-1 |
| カタログ番号GC71502 |
CA/MAO-B-IN-1（化合物78）はヒト脳炭酸無水物酵素（CA）とモノアミン酸化酵素−B（MAO−B）の二重阻害剤であり、IC 50はそれぞれ8.8と7.0 nMである。
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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CA/MAO-B-IN-1 (Compound 78) is a dual inhibitor for human brain carbonic anhydrases (CA) and Monoamine Oxidase-B (MAO-B), with IC50s of 8.8 and 7.0 nM, respectively. CA/MAO-B-IN-1 reveals a human oral absorption of 71.9% through in silico prediction.
CA/MAO-B-IN-1 (12.5-50 μM) reverts formation of ROS, exhibits neuro- and mitochondrial protective effects against Aβ1-42 oligomer-induced neurotoxicity in cells SH-SY5Y[1].
Review for CA/MAO-B-IN-1
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
Review for CA/MAO-B-IN-1
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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