Carebastine |
| カタログ番号GC18198 |
カレバスチンはエバスチンの活性代謝物です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 90729-42-3
Sample solution is provided at 25 µL, 10mM.
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Carebastine is the active metabolite of Ebastine. Carebastine is a histamine H1 receptor antagonist. Carebastine inhibits VEGF-induced HUVEC and HPAEC proliferation, migration and angiogenesis in a dose-dependent manner[1]. Carebastine suppresses the expression of macrophage migration inhibitory factor[2].
References:
[1]. De Luisi A, et al. Anti-angiogenic activity of carebastine: a plausible mechanism affecting airway remodelling. Eur Respir J. 2009 Oct;34(4):958-66.
[2]. Zhao Y, et al. Carebastine, an H1-receptor antagonist, suppresses the expression of macrophage migration inhibitory factor. Clin Exp Dermatol. 2008 Nov;33(6):785-7.
Average Rating: 5 (Based on Reviews and 4 reference(s) in Google Scholar.)
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