CAY10398 (Synonyms: MD 85, PX 089274) |
| カタログ番号GC43147 |
CAY10398は、IC50値が10μMのヒストン脱アセチル化酵素（HDAC1）の阻害剤です。
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Cas No.: 193551-00-7
Sample solution is provided at 25 µL, 10mM.
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CAY10398 is an inhibitor of histone deacetylase (HDAC1) with an IC50 value of 10 µM. Similar potency is observed with trapoxin A and B, whereas trichostatin A is more potent inhibitor of the enzyme. Trichostatin A also selectively inhibits the removal of acetyl groups from the amino-terminal lysine residues of core histones, which modulates the access of transcription factors to the underlying genomic DNA. However, trichostatin A is much more expensive than CAY10398. CAY10398 thus represents a selective and cost-effective compound for the inhibition of HDAC.
Average Rating: 5 (Based on Reviews and 39 reference(s) in Google Scholar.)
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