CCT373566 (Synonyms: CCT373566; CCT 373566; CCT-373566;) |
| カタログ番号GB62229 |
CCT373566は、BCL6の高度に強力な分解剤です（IC50 = 0）。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2378853-66-6
Sample solution is provided at 25 µL, 10mM.
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CCT373566 is a highly potent BCL6 degrader (IC50 =0.7 nM) suitable for sustained depletion of BCL6 in vivo. CCT373566 showed modest in vivo efficacy in a lymphoma xenograft mouse model following oral dosing. The transcriptional repressor BCL6 is an oncogenic driver found to be deregulated in lymphoid malignancies.
Review for CCT373566
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
Review for CCT373566
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