Ceapin-A7 |
| カタログ番号GC61606 |
Ceapin-A7は、ERストレスに対するATF6αシグナル伝達の選択的ブロッカーであり、IC50値は0.59μMです。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2323027-38-7
Sample solution is provided at 25 µL, 10mM.
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Ceapin-A7 is a selective blocker of ATF6α signaling in response to ER stress, with an IC50 of 0.59 μM. Ceapin-A7 can be used to explore both the mechanism of activation of ATF6α and its role in pathological settings[1].
Ceapin-A7 sensitizes cells to ER stress[1].Ceapin (0.6-18.9 μM; 4.5 hours) selectively inhibits ATF6α but not ATF6β[1].
[1]. Ciara M Gallagher, et al. Ceapins are a new class of unfolded protein response inhibitors, selectively targeting the ATF6α branch. eLife. 2016; 5: e11878.
Average Rating: 5 (Based on Reviews and 27 reference(s) in Google Scholar.)
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