Ceefourin 1 |
カタログ番号GC50287 |
セフウリン 1 は、強力で選択性の高い多剤耐性タンパク質 4 (MRP4) 阻害剤です。 Ceefourin 1 は、広範囲の MRP4 基質の輸送を阻害しますが、他の ABC トランスポーターよりも MRP4 に対して高度に選択的です。 Ceefourin 1 はベンゾチアゾールであり、主に高リスク神経芽細胞腫の化学増感剤として使用されます。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 315702-40-0
Sample solution is provided at 25 µL, 10mM.
Selective MRP (multidrug resistance-associated protein) 4 inhibitor (IC50 = 2.6 μM). Selective for MRP4 over P-gp, MRP1 and ABCG2. Sensitizes MRP4 over-expressing cells to SN 38 .
Cheung et al (2014) High-throughput screening identifies Ceefourin 1 and Ceefourin 2 as highly selective inhibitors of multidrug resistance protein 4 (MRP4). Biochem.Pharmacol. 91 97 PMID:24973542
Average Rating: 5
(Based on Reviews and 18 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *