Chromenone 1 |
カタログ番号GC70882 |
Chromenone 1は、強力な骨形成タンパク質(bmp)増強剤です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1639929-29-5
Sample solution is provided at 25 µL, 10mM.
Chromenone 1 is a potent osteogenic bone morphogenetic protein (BMP) potentiator. Chromenone 1 exhibits a unique mode of action as it induces a pronounced, kinase-independent, negative TGFβ feedback that enhances nuclear BMP-Smad signaling outputs.
Chromenone 1 rescues DMH-1-induced cardiogenesis (IC50=0.2 μM) and efficiently stimulates BMP-dependent osteogenesis from C2C12 myoblasts[1].
References:
[1]. Wesseler F, et al. Probing Embryonic Development Enables the Discovery of Unique Small-Molecule Bone Morphogenetic Protein Potentiators. J Med Chem. 2022;65(5):3978-3990.
Review for Chromenone 1
Average Rating: 5
(Based on Reviews and 30 reference(s) in Google Scholar.)Review for Chromenone 1
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