ホーム>>Signaling Pathways>> TGF-β / Smad Signaling>> TGF-β Receptor>>Chromenone 1

Chromenone 1

カタログ番号GC70882

Chromenone 1は、強力な骨形成タンパク質(bmp)増強剤です。

Products are for research use only. Not for human use. We do not sell to patients.

Chromenone 1 化学構造

Cas No.: 1639929-29-5

サイズ 価格 在庫数 個数
1 mg
$117.00
在庫あり
5 mg
$270.00
在庫あり
10 mg
$401.00
在庫あり
25 mg
$682.00
在庫あり

Tel:(909) 407-4943 Email: sales@glpbio.com

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
Chromenone 1 is a potent osteogenic bone morphogenetic protein (BMP) potentiator. Chromenone 1 exhibits a unique mode of action as it induces a pronounced, kinase-independent, negative TGFβ feedback that enhances nuclear BMP-Smad signaling outputs.

Chromenone 1 rescues DMH-1-induced cardiogenesis (IC50=0.2 μM) and efficiently stimulates BMP-dependent osteogenesis from C2C12 myoblasts[1].

References:
[1]. Wesseler F, et al. Probing Embryonic Development Enables the Discovery of Unique Small-Molecule Bone Morphogenetic Protein Potentiators. J Med Chem. 2022;65(5):3978-3990.

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Review for Chromenone 1

Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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