Clindamycin-13C,d3 |
| カタログ番号GC71696 |
Clindamycin-13C,d3は13 Cと重水素標識クリンダマイシンである。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2140264-63-5
Sample solution is provided at 25 µL, 10mM.
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Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References:
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.
[2]. Hodille E, et al. Clindamycin suppresses virulence expression in inducible clindamycin-resistant Staphylococcus aureus strains. Ann Clin Microbiol Antimicrob. 2018 Oct 20;17(1):38.
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