Curcumin-β-D-glucuronide |
| カタログ番号GC63506 |
クルクミン-β-D-グルクロニドは、肝臓組織および門脈血中のクルクミンの経口摂取後の主要な代謝産物です。クルクミン-β-D-グルクロニドは結腸癌の研究に使用できます。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 227466-72-0
Sample solution is provided at 25 µL, 10mM.
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Curcumin-β-D-glucuronide is a major metabolite after oral intake of Curcumin in hepatic tissue and portal blood. Curcumin-β-D-glucuronide can be used for the research of colon cancer[1][2].
Curcumin-β-D-glucuronide (90 mg/kg; i.p. thrice a week for 3 weeks) exhibit potent anti-tumor effects on KRASm/TP53w HCT116 xenograft model[1].
[1]. Ozawa-Umeta H, et, al. Curcumin β-D-glucuronide exhibits anti-tumor effects on oxaliplatin-resistant colon cancer with less toxicity in vivo. Cancer Sci. 2020 May;111(5):1785-1793.
[2]. Ozawa H, et, al. Curcumin β-D-Glucuronide Plays an Important Role to Keep High Levels of Free-Form Curcumin in the Blood. Biol Pharm Bull. 2017;40(9):1515-1524.
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