(d(CH?)?¹,Tyr(Me)²,Dab?,Arg?)-Vasopressin (Synonyms: d(CH2)5[Tyr(Me)2,Dab5]-AVP) |
| カタログ番号GA24029 |
アスパラギン酸5番のイソステリック置換によるオキシトシン、バソプレッシンおよびそれらの類似体のDabへの変換は、常にペプチドの生物活性の劇的な喪失をもたらします。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 176714-12-8
Sample solution is provided at 25 µL, 10mM.
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The isosteric substitution of Asn5 by Dab in oxytocin, vasopressin and their analogs invariably leads to a dramatic loss of the biolical activities of the peptides. In OT or VP antagonists, the exchange generates highly selective and potent OT and V1a receptor antagonists.
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