DC661 |
| カタログ番号GC19485 |
DC661 は、強力なパルミトイルタンパク質チオエステラーゼ 1 (PPT1) 阻害剤であり、オートファジーを阻害し、抗リソソーム剤として作用します。抗がん作用。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1872387-43-3
Sample solution is provided at 25 µL, 10mM.
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DC661 is a potent palmitoyl-protein thioesterase 1 (PPT1) inhibitor, inhibits autophagy, and acts as an anti-lysosomal agent. Anti-cancer activity[1].
DC661 (0.1 and 10 µM) accumulates autophagic vesicles in melanoma cells[1].
Reference:
[1]. Rebecca VW, et al. PPT1 Promotes Tumor Growth and Is the Molecular Target of Chloroquine Derivatives in Cancer. ancer Discov. 2019 Feb;9(2):220-229.
Average Rating: 5 (Based on Reviews and 26 reference(s) in Google Scholar.)
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