Desmethoxyyangonin (Demethoxyyangonin) (Synonyms: Demethoxyyangonin, NSC 68686, NSC 112161, trans-5,6-Dehydrokavain) |
| カタログ番号GC30392 |
デスメトキシヤンゴニン (デメトキシヤンゴニン) は、Piper methysticum (カバ) 植物に見られる 6 つの主要なカバラクトンの 1 つです。 MAO-Bの可逆的阻害剤。
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Cas No.: 15345-89-8
Sample solution is provided at 25 µL, 10mM.
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Desmethoxyyangonin is one of the six major kavalactones found in the Piper methysticum (kava) plant; reversible inhibitor of MAO-B.
[1]. Uebelhack R, et al. Inhibition of platelet MAO-B by kava pyrone-enriched extract from Piper methysticum Forster (kava-kava). Pharmacopsychiatry. 1998 Sep;31(5):187-92. [2]. Baum SS, et al. Effect of kava extract and individual kavapyrones on neurotransmitter levels in the nucleus accumbens of rats. Prog Neuropsychopharmacol Biol Psychiatry. 1998 Oct;22(7):1105-20. [3]. Ma Y, et al. Desmethoxyyangonin and dihydromethysticin are two major pharmacological kavalactones with marked activity on the induction of CYP3A23. Drug Metab Dispos. 2004 Nov;32(11):1317-24.
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