Diphenyl Phosphate-d10 |
カタログ番号GC72504 |
Diphenyl Phosphate-d10 (DPhP-d10) is the deuterium labled Diphenyl Phosphate .
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1477494-97-5
Sample solution is provided at 25 µL, 10mM.
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[2].
References:
[1]. Chen Q, et al. Life Cycle Exposure to Environmentally Relevant Concentrations of Diphenyl Phosphate (DPhP) Inhibits Growth and Energy Metabolism of Zebrafish in a Sex-Specific Manner. Environ Sci Technol. 2021 Oct 5;55(19):13122-13131.
[2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
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