Doramectin aglycone |
カタログ番号GC43562 |
ドラメクチンアグリコンは、線虫においてグルタミン酸とGABAによる塩化物チャネルの開口を増強する二糖類含有の抗寄生薬であるドラメクチンの酸分解生成物であり、その酸触媒加水分解生成物はドラメクチン単糖です。
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Cas No.: 1987883-26-0
Sample solution is provided at 25 µL, 10mM.
Doramectin aglycone is an acid degradation product of doramectin , a disaccharide-containing anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes, and its acid-catalyzed hydrolysis product doramectin monosaccharide . Doramectin undergoes one round of acid-catalyzed hydrolysis to form doramectin monosaccharide which is then hydrolyzed again to remove the remaining saccharide unit and form doramectin aglycone.
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